Changing Healthcare Worldwide

Moving technology forward

Over the past three decades, there has been extensive research into the transdermal delivery of pharmaceuticals and other compounds. Despite many feasibility studies, delivery of drugs through the skin has been limited to a handful of agents such as certain hormones and a few nitrogen-based compounds. The major reason for this limitation is the inherent barrier characteristics of the outermost layer of skin, the stratum corneum.

Early attempts to overcome the barrier were centered on the use of simple solvents or solvent mixtures. These materials, although capable of increasing the penetration of many chemicals across the skin, often caused undesirable side effects, mostly centered on their interaction with plastic polymers making up the delivery device. Existing technology for delivering drugs onto and across the skin can be broken down into two categories: patch or plaster-based, and hydroalcohol gel systems.

TDSC’s groundbreaking research has resulted in a spray-on drug delivery system that addresses a range of unmet needs across a wide spectrum of patient populations. The company’s patented Transdermal Delivery System (TDS) is capable of delivering a variety of drugs by altering the fluidity of the lipid layers in the stratum corneum. TDSC’s spray-on technology temporarily and reversibly alters the alignment of the lipids, allowing the drug compounds to pass through, while protecting the drug from the skin and vice-versa.

Evidence from animal studies and human studies have established that TDSC's system is non-toxic and non-irritating to the skin even after repeated applications.

What distinguishes TDSC's platform technology is its demonstrated ability to produce patentable new products when combined with established drugs. This versatility allows TDSC to incorporate its technology in a wide range of pharmaceutical, cosmeceutical and nutritional uses.